International Space Station (Architecture Edition)
Ground-braking architecture is not necessarily taking place on the ground!
LEGO says this about their Architecture series: "We aim to explore the fascinating worlds of Architecture, Engineering and Construction. Our ambition is to inspire minds of all ages as they learn about the world’s most iconic buildings and structures."
I think that very much covers the most iconic structure mankind has built in space so far:
The INTERNATIONAL SPACE STATION
If you prefere a larger version with more playable features, you'll find it here: